Toshiki Saito, MD, PhD

Center/Department


Clinical Research Center
Director, Department of Regenerative Medicine
Chief, Laboratory of Cell Therapy
Chief, Laboratory of Information System Research
Deputy Director, Department of Clinical Research Management

 

Interest

Tumor immunology
Transplantation biology
Humanized mice

 

Area of Research

Thymic progenitor cells
Humanized mice

 

Contact Information

Toshiki Saito, MD, PhD
National Hospital Organization Nagoya Medical Center
4-1-1 Sannomaru, Naka-ku, Nagoya
Aichi 460-0001, Japan
Office phone: +81-52-951-1111
Fax: +81-52-951-9075
E-mail: toshiki.saito.ae@mail.hosp.go.jp

Preferred contact method: e-mail

 

Research

Dr. Saito’s current research interests focus on establishing a humanized mouse model that precisely reflects patient’s tumor and immune status including cellular immunology. Current projects include 1) transplantation of both hematopoietic stem cells and tumor into immunodeficient mice to mimick patient’s tumor and immune status. 2) Analysis on thymus development which is essential to develop cellular immunology.

 

Recent Award

MMRF 2007 Research Fellow Award

 

Biography

Toshiki Saito received his medical degree in 1994 and a PhD degree in 2003 from University of Tokyo, in Japan, and is a board certified Hematologist and major in hematopoietic stem cell transplantation. After residency training at University of Tokyo Hospital, Showa General Hospital and Kanbara General Hospital, he completed research fellowship at Transplantation Biology Research Center, Massachusetts General Hospital/Harvard Medical School under the supervision of Dr. Megan Sykes. In 2009, he took a position as a Assistant Professor of Hematology and Oncology at University of Tokyo. In 2010, he joined the staff of Nagoya Medical Center as a chief of the laboratory of Cell Therapy at Clinical Research Center.

 

Selected Publications

  1. Fujisaki J, et al. Nature. 2011;474:216-9
  2. Kumagai K, et al. Biol Reprod. 2011;84:682-8
  3. Saito TI, et al. J Immunol 2010;185:2099-105
  4. Saito TI, et al. Exp Hematol 2010;38:333-9
  5. Saito TI, et al. Exp Hematol 2006;34:1270-6
  6. Saito T, et al. Immunity 2003;18:675-85

Complete list of all publications.

 

Investigators

None

 

Trainees

Masahiro Sekimizu, MD